Eczema & genetics

Why eczema
& genetics?

Atopic eczema, also known as 'atopic dermatitis' or simply 'eczema' is an itchy skin condition which most often begins in childhood but can continue throughout adult life.

Mild eczema may be a minor irritation, but for people for whom it is severe or widespread, the condition has a profound effect on every aspect of life, including school, work and relationships.

Eczema may occur alone, or with other ‘atopic’ disorders, including asthma, hay fever or food allergies.

Recent research has also shown possible links with ADHD and depression.

Eczema is a
‘complex trait’

Eczema is caused by a mixture of genetics (your DNA, how your skin is made) and environmental effects - this is called a complex trait.

Our research has shown that some genes strengthen the skin, to make a protective barrier; when these genes are not working properly, the skin becomes inflamed, leading to eczema.

Read More

Atopic eczema - clinical information and treatment

RCP Journals


Molecular genetic mechanisms in atopic eczema

J Path


Food allergies and the role your skin plays

The Conversation